CF Carriers: What We Thought We Knew, and What We’re Learning

From Living With Cystic Fibrosis · 00:45:25

Show by Laura Bonnell

CF Carriers: What We Thought We Knew—and What We’re LearningWhat Does It Really Mean to Be a CF Carrier? And the Heart Behind the Doctor.For years, we’ve been told that CF carriers are healthy. But what if the story is more complicated?I met Professor Nick Simmonds of Royal Brompton Hospital and Imperial College London at the European Cystic Fibrosis Society Conference (ECFS) in Lisbon, Portugal, in 2025. His presentation explored CF carriers, CFTR function, and what emerging research may be teaching us about the health of people who carry a CFTR mutation.In this conversation, Professor Simmonds explores some of the most intriguing questions in cystic fibrosis research, including whether having one CFTR mutation may have health implications for some people. His work has focused on complex CF diagnoses, CFTR-related disorders, and the development of new CF therapies. He has also played an important role in international clinical trials, the ECFS Diagnostic Network and Clinical Trials Network, and the UK CF Registry.But this conversation goes beyond the science.Professor Simmonds shares his deep love for the CF community, his passion for doing more for patients and families, and why he considers his patients family. His commitment to the people behind the diagnosis offers a heartfelt look at the personal side of medicine and the relationships that make this work so meaningful.And when I asked him who his heroes are in the CF community, I was pleasantly surprised with his answer! He named two remarkable women! Hear what he has to say about them. Join us for a conversation about groundbreaking questions in CF research, the future of our understanding of CFTR, and the extraordinary connections between a doctor and the community he cares so deeply about.To learn more about Dr. Bonnie Ramsey and Professor Margaret Hodson follow these links: Dr. Bonnie Ramsey and Dr. Margaret Hodson Like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: [email protected] Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredNew: Shop our merchandise! https://thebonnellfoundation.org/product-shop/Thanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

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