Can You Prevent Alzheimer’s? Dr. Josh Helman on Brain Health

From The Well Known Podcast: Exploring Longevity, Biohacking, and Alternative Medicine · 32:42

Show by Shannon Conklin

What if we started thinking about Alzheimer’s prevention decades before memory problems ever appeared?This conversation is personal for Shannon Conklin. After watching Alzheimer’s affect multiple generations of her family, she sits down with Harvard-trained physician Dr. Josh Helman to talk about brain health, dementia, and what we can do today to support our cognitive health tomorrow.They get into the difference between Alzheimer’s and dementia, what genetic testing can tell us, and why Dr. Josh believes we need to look beyond amyloid plaques when discussing brain health.And because brain health doesn’t exist in a vacuum, they’re talking about everything from deep sleep and exercise to mitochondrial health, inflammation, nutrition, GLP-1 medications, and creatine.Shannon also shares her own experience with genetic testing, her family’s history with Alzheimer’s, and the questions driving her interest in prevention.It’s a conversation about asking better questions, understanding your options, and taking brain health seriously long before symptoms appear.What You’ll LearnThe difference between Alzheimer’s disease and dementiaHow genetics, including APOE4, may influence Alzheimer’s riskWhy sleep, exercise, nutrition, and social connection matter for brain healthWhat Dr. Josh thinks about inflammation, amyloid, and individualized careThe potential connection between insulin resistance and cognitive healthWhy creatine and mitochondrial health are part of the brain health conversationHow to approach prevention when Alzheimer’s runs in your familyConnect with Dr. Josh HelmanWebsite: drjosh.com | Podcast: drjosh.com/podcast | Social: @GreenBrainsMDConnect with Shannon:Grab the Magnesium Cheat Sheet here: https://thewellknownpodcast.com/resourcesChapters:00:00 Why Alzheimer's prevention is personal for Shannon01:00 Alzheimer's vs. dementia: What's the difference?02:00 How Alzheimer's is diagnosed today03:00 Amyloid and brain inflammation06:00 Genetics, and individual risk08:35 Mitochondrial health and the brain09:30 Deep sleep and the glymphatic system11:00 What can you do before symptoms start?13:00 Detoxification and colon hydrotherapy15:00 Lectins and emerging treatment approaches18:00 Exploring potential underlying contributors20:00 Nutrition and the gut-brain connection22:00 GLP-1 medications and metabolic health24:00 Why Dr. Josh emphasizes lifestyle25:15 Creatine and cognitive health27:15 Mitochondria, exercise, and prevention30:30 Getting proactive about brain health31:15 What does wellness mean to Dr. Josh?

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